Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0321212
PubChem CID
Molecular Formula
C15H15NO2S
Molecular Weight
273.357 g/mol
Synonyms/Alias
[modafinil; 68693-11-8; Provigil; Modiodal; 2-[(diphenylmethyl)sulfinyl]acetamide; 2-(Benzhydrylsulfinyl)acetamide; Modafinilum [Latin]; 2-benzhydrylsulfinylacetamide; modaphonil; Modafinilo [Spanish]...
InChI Key
YFGHCGITMMYXAQ-UHFFFAOYSA-N
InChI
InChI=1S/C15H15NO2S/c16-14(17)11-19(18)15(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10,15H,11H2,(H2,16,17)
IUPAC Name
2-benzhydrylsulfinylacetamide
CAS Number
68693-11-8

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

34 35 0 0 0 0 0 0 0 0999 V2000
0.3678 3.4248 0.6360 C 0 0 0 0 0 0 0 0 0 0 0 0
0.0109 2.9191 -0.6158 C 0 0 0 0 0 0 0 0 0 0 0 0
-0.0636 1.538...

Experimental Data

Activity Data

Target Ion Channel
Intermediate conductance calcium activated potassium channel protein 4
Uniprot Accession Number
Function
Inhibitor
Species
Mus musculus (Mouse)
IC50
IC50: 6.8 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
pH 7.4
Holding Potential
−100 to 100 mV mV
Temperature
Room Temperature
Test Method
Patch-clamping
Test Species
mice muscle cell

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
19
Rotatable Bonds
5
logP
2.01
Complexity
76.9308
TPSA (Ų)
60.16
H-Bond Donors
1
H-Bond Acceptors
2
Ring Count
2
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